Linoleic acid and alpha-linolenic acid metabolism

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Circulating linoleic acid and alpha-linolenic acid and glucose metabolism: the Hoorn Study

PURPOSE Data on the relation between linoleic acid (LA) and alpha-linolenic acid (ALA) and type 2 diabetes mellitus (T2DM) risk are scarce and inconsistent. The aim of this study was to investigate the association of serum LA and ALA with fasting and 2 h post-load plasma glucose and glycated hemoglobin (HbA1c). METHOD This study included 667 participants from third examination (2000) of the p...

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Effects of conjugated linoleic acid on linoleic and linolenic acid metabolism in man.

Evidence from animal studies suggests that conjugated linoleic acid (CLA) modulates plasma and tissue appearance of newly synthesized PUFA. The effects of a 1.2g (0.5 % energy) daily intake of the cis-9,trans-11 (c9,t11) isomer of CLA, trans-10,cis-12 (t10,c12) isomer of CLA or olive oil (placebo) on linoleic acid (LA) and linolenic acid (LNA) metabolism in healthy human volunteers was investig...

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Alpha-linolenic acid

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α-Linolenic acid, linoleic acid and heart failure in women.

α-Linolenic acid (18 : 3n-3) intake and linoleic acid (18 : 2n-6) intake have been associated with lower rates of CHD, though results have not been consistent. The relationship of these fatty acids with incident heart failure (HF) is not well established. We examined the hypothesis that women with higher intakes of 18 : 3n-3 and 18 : 2n-6 would have lower rates of HF hospitalisation and mortali...

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Oleic acid versus linoleic and α-linolenic acid. different effects on Ca2+ signaling in rat thymocytes.

BACKGROUND Oleic acid is the principal fatty acid of olive oil composition and is reported to play a crucial role in its healthy aspects. However, the detailed mechanism of action is poorly understood. AIMS This study aims to elucidate the role of oleic acid in calcium signaling in rat thymocytes, in comparison to linoleic and linolenic acid. METHODS Fatty acids were applied to thymocytes i...

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ژورنال

عنوان ژورنال: Reactome - a curated knowledgebase of biological pathways

سال: 2012

ISSN: 1934-1792

DOI: 10.3180/react_121284.1